
簡要描述:Recombinant Human IL-13 Protein(C-6His)is produced by our Mammalian expression system and the target gene encoding Gly35-Asn146 is expressed with a 6His tag at the C-terminus.
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Product Category詳細介紹
| 品牌 | absin | 純度 | Greater than 95% as determined by reduci |
|---|---|---|---|
| 貨號 | abs04079 | 規(guī)格 | 10ug |
| 供貨周期 | 現(xiàn)貨 | 主要用途 | is produced by our Mammalian expression |
| 應用領(lǐng)域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
Recombinant Human IL-13 Protein(C-6His)
| 產(chǎn)品描述 | |
| 描述 | Recombinant Human Interleukin-13 is produced by our Mammalian expression system and the target gene encoding Gly35-Asn146 is expressed with a 6His tag at the C-terminus. |
| 別名 | Interleukin-13蛋白;IL-13蛋白;Interleukin-13; IL-13; |
| 種屬 | Human |
| 來源 | Human Cells |
| 形態(tài) | Lyophilized from a 0.2 μm filtered solution of PBS,PH7.4. |
| 儲存/保存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 性能 | |
| 序列 | LTCLGGFASPGPVPPSTALRELIEELVNITQNQKAPLCNGSMVWSINLTAGMYCAALESLINVSG CSAIEKTQRMLSGFCPHKVSAGQFSSLHVRDTKIEVAQFVKDLLLHLKKLFREGQFNVDHHHHHH |
| 標簽 | C-6His |
| 純度 | Greater than 95% as determined by reducing SDS-PAGE. |
| 內(nèi)毒素水平 | Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. |
| 活性 | Measured in a cell proliferation assay using TF-1 human erythroleukemic cells The ED50 for this effect is 1.5-4.5 ng/ml. |
| 溶解方法 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 靶標 | |
| 背景說明 | Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. |
| Accession | AAH96139 |
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