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詳細介紹
| 品牌 | absin | 純度 | Greater than 95% as determined by reduci |
|---|---|---|---|
| 貨號 | abs04106 | 規格 | 10ug |
| 供貨周期 | 現貨 | 主要用途 | is produced by our Mammalian expression |
| 應用領域 | 化工,生物產業,農林牧漁,制藥/生物制藥,綜合 |
Recombinant Human MMP-3 Protein(C-6His)
| 產品描述 | |
| 描述 | Recombinant Human Matrix Metalloproteinase-3 is produced by our Mammalian expression system and the target gene encoding Tyr18-Cys477 is expressed with a 6His tag at the C-terminus. |
| 別名 | Matrix Metalloase-3蛋白；MMP-3蛋白;Stromelysin-1; SL-1; Matrix metalloproteinase-3; MMP-3; Transin-1; MMP3; STMY1 |
| 種屬 | Human |
| 來源 | Human Cells |
| 形態 | Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, 0.05% Brij35, 10% Glycerol, pH 7.5. |
| 儲存/保存方法 | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| 性能 | |
| 序列 | YPLDGAARGEDTSMNLVQKYLENYYDLEKDVKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSD TLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPL TFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNL FLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDS |
| 標簽 | C-6His |
| 純度 | Greater than 95% as determined by reducing SDS-PAGE. |
| 內毒素水平 | Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. |
| 靶標 | |
| 背景說明 | MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling.[3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. |
| Accession | P08254 |
| 研究領域 | |
| 研究領域 | CancerInvasion/microenvironmentAngiogenesisECM enzymesMMPs CancerInvasion/microenvironmentECMExtracellular matrixMMPs CancerTumor biomarkersEnzymesMMPs CardiovascularAtherosclerosisThrombosisOther Proteolysis / UbiquitinProteolytic enzymesMetalloproteaseMMPs NeuroscienceDiseases NeuroscienceProcesses Signal TransductionCytoskeleton / ECMExtracellular MatrixMMPECM Enzymes CardiovascularAngiogenesisAdhesion / ECMMatrix MetalloproteinasesMMP |
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