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1-EBIO 10045-45-1 1-Ethyl-2-benzimidazolinone is a calium channel agonist.
(-)MK-801 maleate 121917-57-5 (-)-MK 801 Maleate is the enantiomer of (+)-MK-801; (+)-MK-801 is a highly potent and selective non-competitive NMDA glutamate receptor antagonist .
(+)MK-801 maleate 77086-22-7 Dizocilpine maleate(MK 801) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM
(+)-JQ-1 1268524-70-4 (+)-JQ1 is a BET bromodomain inhibitor, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family.
(+)-Bicuculline 485-49-4 (+)-Bicuculline is an antagonist of the GABAA receptor.
17-AAG 75747-14-7 Tanespimycin (17-AAG)是一種有效的HSP90抑制劑,無細胞試驗中IC50為5 nM,作用于來自腫瘤細胞的HSP90比作用于來自正常細胞HSP90結合親和力高100倍。
Rapamycin 53123-88-9 作用于HEK293細胞,抑制內源性mTOR活性,IC50為~0.1nM,而iRap和AP21967 作用時,IC50分別為~5 nM 和~10 nM。Rapamycin處理釀酒酵母,誘導細胞周期停在G1/S期,且抑制翻譯。
Y-27632 146986-50-7 Y-27632 is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM in a cell-free assay, exhibits 200-fold selectivity over Others kinases, including PKC