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詳細介紹
| 品牌 | absin | 純度 | Greater than 95% as determined by reduci |
|---|---|---|---|
| 貨號 | abs04115 | 規格 | 10ug |
| 供貨周期 | 現貨 | 主要用途 | is produced by our Mammalian expression |
| 應用領域 | 化工,生物產業,農林牧漁,制藥/生物制藥,綜合 |
Recombinant Human NEU-1 Protein(C-6His)
| 產品描述 | |
| 描述 | Recombinant Human Sialidase-1 is produced by our Mammalian expression system and the target gene encoding Glu48-Leu415 is expressed with a 6His tag at the C-terminus. |
| 別名 | Sialidase-1蛋白；NEU-1蛋白;Sialidase-1; Acetylneuraminyl Hydrolase; G9 Sialidase; Lysosomal Sialidase; N-Acetyl-Alpha-Neuraminidase 1; NEU1; NANH |
| 種屬 | Human |
| 來源 | Human Cells |
| 形態 | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl,10% Glycerol, pH 7.4. |
| 儲存/保存方法 | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| 性能 | |
| 序列 | ENDFGLVQPLVTMEQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALR RSMDQGSTWSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDD GVSWSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASWRY GSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDAC |
| 標簽 | C-6His |
| 純度 | Greater than 95% as determined by reducing SDS-PAGE. |
| 內毒素水平 | Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. |
| 靶標 | |
| 背景說明 | Sialidase-1 belongs to the N-acetyl-a neuraminidase family. Sialidase-1 is expressed in many tissues; it is highly expressed in the pancreas, and weakly expressed in the brain. Sialidase-1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. Deficiencies in the human enzyme Sialidase-1 leads to sialidosis, a rare lysosomal storage disease. Sialidase-1 has been shown to interact with Cathepsin A (protective protein), β-galactosidase and N-acetylgalactosamine-6-sulfate sulfatase in a multienzyme complex. |
| Accession | Q99519 |
| 研究領域 | |
| 研究領域 | MetabolismPathways and ProcessesMetabolic signaling pathwaysAmino acid metabolism MetabolismPathways and ProcessesMetabolic signaling pathwaysEnergy transfer pathwaysEnergy Metabolism NeuroscienceProcesses Signal TransductionMetabolismAmino Acids Signal TransductionMetabolismEnergy Metabolism |
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