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詳細介紹
| 品牌 | absin | 純度 | Greater than 95% as determined by reduci |
|---|---|---|---|
| 貨號 | abs04107 | 規格 | 10ug |
| 供貨周期 | 現貨 | 主要用途 | is produced by our Mammalian expression |
| 應用領域 | 化工,生物產業,農林牧漁,制藥/生物制藥,綜合 |
Recombinant Human TIMP-1 Protein(C-6His)
| 產品描述 | |
| 描述 | Recombinant Human Tissue Inhibitor of Metalloproteinases 1 is produced by our Mammalian expression system and the target gene encoding Cys24-Ala207 is expressed with a 6His tag at the C-terminus. |
| 別名 | TIMP-1蛋白;Metalloproteinase Inhibitor 1; Erythroid-Potentiating Activity; EPA; Fibroblast collagenase Inhibitor; Collagenase Inhibitor; Tissue Inhibitor of Metalloproteinases 1; TIMP-1; TIMP1; CLGI; TIMP |
| 種屬 | Human |
| 來源 | Human Cells |
| 形態 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| 儲存/保存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 性能 | |
| 序列 | CTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIRFVYTPA MESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKTYTVGCEECTVF PCLSIPCKLQSGTHCLWTDQLLQGSEKGFQSRHLACLPREPGLCTWQSLRSQIAVDHHHHHH |
| 標簽 | C-6His |
| 純度 | Greater than 95% as determined by reducing SDS-PAGE. |
| 內毒素水平 | Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. |
| 溶解方法 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 靶標 | |
| 背景說明 | Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16. TIMP-1 does not act on MMP-14. |
| Accession | P01033 |
| 研究領域 | |
| 研究領域 | CancerInvasion/microenvironmentAngiogenesisECM enzymesTIMPs CancerInvasion/microenvironmentECMExtracellular matrixTIMPs Proteolysis / UbiquitinProtease inhibitorsMetalloprotease inhibitorsTIMPs Signal TransductionCytoskeleton / ECMExtracellular MatrixTIMP1 / TIMP2ECM Enzymes CardiovascularAngiogenesisAdhesion / ECMMatrix MetalloproteinasesTIMP |
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